![proteus mirabilis proteus mirabilis](https://phil.cdc.gov/PHIL_Images/1046/1046_lores.jpg)
Additionally, high-mortality (up to 50% in elderly patients) bacteremia and sepsis cases associated with P. CAUTIs typically occur in elderly patients who undergo long-term catheterization ( Schaffer & Pearson, 2015 Milo et al., 2017). mirabilis causes between 10% and 44% of catheter-associated urinary tract infections (CAUTIs), which are among the world’s most abundant nosocomial infections.
![proteus mirabilis proteus mirabilis](https://i.ytimg.com/vi/r0k3ImatLmg/mqdefault.jpg)
mirabilis often occur in the eyes, mouth, and intestines, yet are predominantly associated with urinary tract infections (UTIs) ( Schaffer & Pearson, 2015 Armbruster, Mobley & Pearson, 2018). Proteus mirabilis, a ubiquitous Gram-negative bacterium, is most frequently isolated from the gastrointestinal tracts of humans and animals ( O’Hara, Brenner & Miller, 2000 Drzewiecka, 2016). Predicted structural proteins in Privateer appear to have evolutionary relationships with other prolate podophages, in particular the Kuraviruses Comparative analysis demonstrated Privateer shares 83% nucleotide similarity with Cronobacter phage vB_CsaP_009, but low nucleotide similarity with other known phages. Cesium-gradient purified Privateer particles analyzed via LC-MS/MS verified the presence of several predicted structural proteins, including a longer, minor capsid protein apparently produced by translational frameshift. Genes encoding DNA replication proteins, DNA modification proteins, four tRNAs, lysis proteins, and structural proteins were identified. In the 90.7 kb Privateer genome, 43 functions were assigned for the 144 predicted protein-coding genes. Basic characterization assays demonstrated Privateer has a latent period of ~40 min and average burst size around 140.
![proteus mirabilis proteus mirabilis](https://europepmc.org/articles/PMC4638163/bin/nihms-724705-f0003.jpg)
mirabilis bacteriophage Privateer, a prolate podophage of the C3 morphotype isolated from Texas wastewater treatment plant activated sludge. The Gram-negative bacterium Proteus mirabilis causes a large proportion of catheter-associated urinary tract infections, which are among the world’s most common nosocomial infections.